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Işıntaş M, Ak M, Erdem M et al (2019) Event-related potentials in major depressive disorder: the relationship between P300 and treatment response. Inoue Y, Nanba K, Kojima K et al (2013) P300 abnormalities in patients with severe sleep apnea syndrome. Hrubos-Strom H, Nordhus I, Einvik G et al (2012) Obstructive sleep apnea, verbal memory, and executive function in a community-based high-risk population identified by the Berlin Questionnaire Akershus Sleep Apnea Project. Hidese S, Ota M, Wakabayashi C et al (2016) Effects of chronic l-theanine administration in patients with major depressive disorder: an open-label study. Goodin DS, Aminoff MS (1992) Evaluation of dementia by event-related potentials. Ideggyogy Sz 65(5–6):181–194ĭemir S, Çelikel FÇ, Taycan SE et al (2013) Neuropsychological assessment in conversion disorder. 26(2):120–122Ĭsábi E, Várszegi M, Sefcsik T et al (2012) Effect of two month positive airway pressure therapy on the structure of sleep, cognitive function and anxiety. 47(3):191–198īhattacharyya N (2012) Functional limitations and workdays lost associated with chronic rhinosinusitis and allergic rhinitis. 43:180–184īakar E, Bakar B (2010) Neuropsychological assessment of adult patients with shunted hydrocephalus. Allergy 60(4):452–458Īndrews AE, Bryson JM, Rowe-Jones JM (2005) Site of origin of nasal polyps: relevance to pathogenesis and management. Am J Otolaryngol 36(1):47–51Īlobid I, Benítez P, Bernal-Sprekelsen M et al (2005) Nasal polyposis and its impact on quality of life: comparison between the effects of medical and surgical treatments. These cognitive functions improve after the patients undergo endoscopic sinus surgery to treat their CRSwNP.Īdnane C, Adouly T, Zouak A et al (2015) Quality of life outcomes after functional endoscopic sinus surgery for nasal polyposis. In conclusion, the results of this study indicate that chronic rhinosinusitis with nasal polyposis (CRSwNP) has negative effects on cognitive functions, such as the ability to focus and maintain concentration. The preoperative and postoperative latency values for P300 showed a significant difference ( p = 0.029), whereas the preoperative and postoperative amplitude values for P300 did not differ ( p = 0.096). The postoperative P300 latency values improved in 19 (63%) patients.
The mean preoperative Stroop test (23.16 ± 5.30), visual aural digit span test (24.68 ± 3.52), and serial digit learning test (16.18 ± 5.35) scores were showed significant improvement compared with mean postoperative Stroop test (21.12 ± 5.69), visual aural digit span test (26.45 ± 2.98), and serial digit learning test (19.31 ± 4.47) scores ( p = 0.047, p = 0.022, p = 0.005 respectively). Only 22 patients completed the neuropsychological tests. Preoperative nasal congestion accompanied with impaired concentration were detected in 27 patients (90%), and these symptoms recovered in all these patients after treatment ( p = 0.035) (correlation coefficient 0.4). On the Visual Analog Scale, all symptoms showed significant postoperative improvement in all patients ( p < 0.001 for all symptoms). A total of 30 patients were included in the study. Three months after treatment, the tests done before surgery were repeated and the results were compared. Brief symptom inventory test, Stroop test, visual aural digit span, serial digit learning test and P300 test were used to evaluate cognitive functions. Symptoms of nasal congestion, loss of smell, postnasal drip, headaches, snoring, concentration difficulties and blunted affect were evaluated by Visual Analog Scale. Patients with chronic rhinosinusitis with nasal polyposis causing bilateral total or near total nasal obstruction were enrolled in the study. The aim of this study was investigate the effect of nasal obstruction related to chronic rhinosinusitis with nasal polyposis on cognitive functions. Chronic rhinosinusitis with nasal polyposis is a chronic inflammatory disease of the respiratory mucosa of the nasal cavity and paranasal sinuses.